EMETROPİ NEDİR
Akomodasyon (uyum) yapmayan bir gözde sonsuz olarak nitelendirilen mesafe olan 6 m’den uzaktaki bir objeden optik eksene paralel olarak gelen ışık ışınlarının retina düzlemi üzerine odaklanmasıdır. Emetrop bir gözde sonsuzdan optik eksene paralel olarak gelen ışınlar retinada odaklanır.
AMETROPİ NEDİR
Akomodasyon yapmayan bir gözde 6 m’den uzaktaki bir objeden gelen paralel ışık ışınları- nın retina düzlemi dışında bir düzlemde odaklanmasıdır. Işınların retinanın önünde bir noktaya odaklaması durumuna miyopi, arkasında odaklaması durumuna hipermetropi denirken, ışınların noktasal olarak odaklanamaması durumuna ise astigmatizma denir. Astigmatizma kendi içerisinde, ışınların retinanın önünde veya arkasında odaklanamama durumuna göre miyopik veya hipermetropik astigmatizma olarak alt gruplara ayrılır.
Ametropi;
Gözün ön arka uzunluğundaki farklılıklar
Kırıcı yüzeylerin eğimindeki farklılıklar
Kırılma indisi farklılıkları
Lensin yerleşiminde farklılıklar veya
Yukarıdaki faktörlerden birkaçının bir araya gelmesi sonucu gelişebilir.
AMETROPİ TÜRLERİ
Ametropiler şu şekilde sınıflandırılabilir:
Sferik ametropiler : Hipermetropi, Miyopi
Asferik (silindirik) ametropiler : Astigmatizma
Basit astigmatizma : Hipermetropik, Miyopik
Bileşik astigmatizma : Hipermetropik, Miyopik, Karma
Doğumda gözün ön arka çapı yaklaşık 18 mm’dir. Bu değer 3 yaşında 23 mm’ye çıkar. 3-14 yaşlar arasında ise ön arka uzunluk, yılda ortalama 0,1 mm artar. Daha sonra normal şartlarda gözün uzunluğunda bir değişiklik olmaz. Yeni doğanlarda siklopleji yapılarak saptanan refraksiyon sonuçları ortalama (+2,00) D olarak bulunmuştur.
2-6 yaş grubunda % 80 hipermetropi, % 5 miyopi, % 15 emetropi vardır. Ama bunların sadece % 10-20 kadarı tashih gerektirir. Yetişkinde ise ortalama değer (0) D’dir. Yetişkin yaşlarda başlayan miyopi nedeninin ön arka uzunluktaki artış olduğu belirlenmiştir. Bu nedenle gözün erken çocukluktaki büyümesi haricinde yetişkin yaşlarda da yeniden büyüme potansiyeline sahip olduğu düşünülmektedir.
Hayvanlarda yapılan deneysel çalışmalarda göze ışık gelmesinin engellenmesi ile miyopi geliş- tiği saptanmıştır. Miyopi gelişme nedeninin, ışıkla uyarılmayan retinada birtakım maddelerin yapımının azalmasına bağlı olarak gözün büyümesi üzerindeki frenleme mekanizmalarının ortadan kalkması olduğu düşünülmektedir. Sonuç olarak gözün ekseninde uzama meydana gelmekte ve miyopi gelişmekte denilmektedir.
Bebeklik döneminde retinada görüntü oluşumunun engellenmesi gözün büyüme işlemini etkiler. Hayvan deneylerinde bu durumda gözün ön arka uzunluğunun yaklaşık 4 mm uzadığı ve (-12.00) D miyopi oluştuğu gösterilmiştir. çeşitli nedenler-e bağlı olarak gözün kapatıldığı dolayısıyla retinada görüntü oluşumunun engellendiği yeni doğanlarda kapatılan gözde miyopi gelişmiş ve bu gözlerde yapıları ön kamara derinliği ve lens kalınlığının normal olduğu; lens arka yüzü - retina mesafesinin ise anlamlı ölçülerde arttığı gösterilmiştir. Aynı mekanizma ile hayatın ilk yıllarındaki yüksek kırma kusurları görmeyi bulandırarak miyop ye sebep olabilir.
Aşırı akomodasyonun da miyopinin gelişimini hızlandırdığı düşünülmektedir. Yoğun bir şekilde yakın çalışma yapan kişilerde miyopide bir artış söz konusudur. Hayvan ve insan deneylerinde ilaçlarla akomodasyonun engellenmesi sonucu miyopi ilerlemesinin yavaşladığı gösterilmiştir.
REFRAKTİF KUSURLARDA GENETİK GEÇİŞ
Refraksiyon kusurlarının genetik geçişli olduğunu gösteren bazı çalışmalar vardır. Miyopi veya yüksek hipermetropi taşıyan aileler bildirilmiş ve genetik bir geçiş olduğu savunulmuştur. Ancak genetik geçiş konusunda halen kesin bir şey söylenememektedir. Anormal ön arka uzunluğa bağlı miyopi gibi ametropilerde multifaktöriyel (birçok faktöre bağlı) kalıtım sözkonusudur. Bunlarda otozomal resesif, otozomal dominant ve cinsiyete bağlı kalıtımlar bildirilmiştir.
REFRAKTİF KUSURLARIN TOPLUMDA GÖRÜLME ORANI
Refraktif kusurların dağılımı ile ilgili pek çok araştırma yapılmıştır. Bu çalışmalarda Japonya, İsrail ve Çin’de miyopinin, zencilerde hipermetropinin sık olduğu gösterilerek ırkın önemli bir faktör olduğu belirtilmiştir. Okul taramaları şeklinde yapılan çalışmalarda %10-15 çocukta refraksiyon kusuru belirlenmiş. Bunların %40-50’inde astigmatizma, 25-35’inde miyopi, % 15-25’inde ise hipermetropi tespit edilmiştir. Gebelik esnasında refraksiyon kusuru, kornea eğrilik ve kalınlığı, akomodasyon amplitüdü, Akomodatif Konverjans/ Akomodasyon (AK/A) oranları açısından anlamlı değişikliklerin ortaya çıkmadığı bildirilmiştir.
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